Invalidity dossier

US 12239333

Single insertion delivery system for treating embolism and associated systems and methods

Current assignee: Unified Patents

Added 5/12/2026, 11:39:10 PM

IndustryMedical (M)

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Patent summary

Title, assignee, inventors, filing/issue dates, abstract, and a plain-language overview of the claims.

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Here's a concise summary of US Patent 12239333:

  • Title: Single insertion delivery system for treating embolism and associated systems and methods
  • Assignee: Inari Medical Inc
  • Inventors: Richard Quick, Benjamin Edward Merritt, John Coleman Thress, Paul Lubock, Thomas M. Tu
  • Filing Date: October 30, 2023
  • Issue Date: March 4, 2025
  • Abstract: Systems and methods are disclosed for the intravascular treatment of clot material within a blood vessel of a human patient. A method can involve engaging an interventional device with clot material in a blood vessel and withdrawing both the device and a portion of the clot material through a guide catheter. The catheter system may include an attachment/valve member coupled to a proximal portion of the guide catheter. The method can further include unsealing this attachment/valve member to facilitate withdrawal of the interventional device without significant retention of clot material. The guide catheter can then be resealed and aspirated before advancing another interventional device to remove additional clot material.

Plain-Language Overview of Independent Claims:

Claim 1:
This claim describes a method for removing clot material from a patient's blood vessel. It involves:

  1. Inserting a guide catheter into the blood vessel until its distal end is near the clot.
  2. Advancing an interventional device through the guide catheter to engage the clot.
  3. Connecting an attachment member to the guide catheter, where the attachment member has a hemostasis valve and a branch lumen for aspiration.
  4. Retracting the interventional device and clot into the guide catheter while simultaneously aspirating through the guide catheter.
  5. Opening the hemostasis valve of the attachment member by inserting a first valve insert into it.
  6. Withdrawing the interventional device out of the patient through the attachment member and the inserted first valve, thereby creating a continuous lumen to prevent clot material from being stripped.
  7. Removing the first valve insert and replacing it with a second valve insert.
  8. Tightening the second valve insert to seal around a component (like a guidewire) that remains in the guide catheter.
  9. Aspirating the guide catheter again, through the branch lumen of the attachment member, to remove any remaining clot material before the interventional device is re-advanced.

Claim 9:
This claim describes a method for intravascular treatment of clot material that focuses on an attachment member with an actuated valve. It involves:

  1. Inserting a guide catheter into a blood vessel and advancing an interventional device to engage clot material.
  2. Coupling an attachment member to the guide catheter. This attachment member contains a tubular member forming a central lumen and an actuation mechanism to collapse and seal the tubular member.
  3. Retracting the interventional device and captured clot into the guide catheter while simultaneously aspirating through the guide catheter.
  4. Determining if more clot removal passes are needed. If so:
  5. Actuating the attachment member (e.g., pressing buttons) to open the tubular member, ensuring a continuous lumen of generally constant diameter through the attachment member.
  6. Withdrawing the interventional device through this opened attachment member.
  7. Returning the attachment member to its sealed state (collapsing the tubular member).
  8. Aspirating the guide catheter through a branch lumen of the attachment member to clear residual clot.

Claim 16:
This claim details a specific type of attachment member for a catheter system. It comprises:

  1. A housing with a first lumen designed to receive a component of the catheter system (like a guide catheter).
  2. A branch portion with a second lumen that connects to the first lumen and is configured for aspiration.
  3. A valve located within the first lumen, which includes a tubular member defining a central lumen and an actuation mechanism. This actuation mechanism is designed to collapse the tubular member to seal the central lumen and to expand it to unseal the central lumen, allowing for the passage of an interventional device without significant change in diameter or stripping of clot material.

Legal Status and Litigation:

US Patent 12239333 is currently Active and was granted on March 4, 2025.

As of April 26, 2026, there is a PTAB case IPR2026-00215 filed (Pending) litigation related to this patent.

A search of the CAFC 2026 dockets did not reveal any specific cases directly involving patent 12239333. The search provided general information about scheduled cases for May, June, and July 2026, but no mention of this specific patent.

Generated 5/28/2026, 12:46:27 PM