US 12371685

US Patent 12371685 (specifically US12371685B2) concerns PH20 polypeptide variants.

Here is a summary of the patent based on the provided authoritative text:

• Title: PH20 polypeptide variants with a modification at position 324 of the PH20 polypeptide and a method of making thereof
• Assignee: Halozyme Inc; Halozyme Therapeutics Inc
• Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
• Filing Date: 2023-06-23
• Issue Date (Publication Date): 2025-07-29
• Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.

Plain-Language Overview of Independent Claims:

The provided "Full patent text" does not contain the complete, numbered claims section. Therefore, I cannot provide a plain-language overview of each independent claim with authoritative information at this time.

Legal Status and Litigation:

• The patent is Active and is expected to expire on 2033-08-10.
• There is a PTAB case PGR2025-00087 filed (Pending).
• First worldwide family litigation filed is also noted.

Regarding CAFC 2026 dockets for US patent 12371685, no specific cases were found in the provided information or from a general search for CAFC 2026 dockets referencing this patent number. The noted litigation is at the PTAB (Patent Trial and Appeal Board) level.
The user asked for CAFC 2026 dockets, and the provided patent information indicates a PTAB case, not a CAFC case directly related to 2026 dockets.US Patent 12371685 (specifically US12371685B2) concerns PH20 polypeptide variants.

Here is a summary of the patent based on the provided authoritative text:

• Title: PH20 polypeptide variants with a modification at position 324 of the PH20 polypeptide and a method of making thereof
• Assignee: Halozyme Inc; Halozyme Therapeutics Inc
• Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
• Filing Date: 2023-06-23
• Issue Date (Publication Date): 2025-07-29
• Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.

Plain-Language Overview of Independent Claims:

The provided "Full patent text" does not contain the complete, numbered claims section. Therefore, a plain-language overview of each independent claim cannot be provided with authoritative information at this time.

Legal Status and Litigation:

• The patent is Active and is expected to expire on 2033-08-10.
• A PTAB case, PGR2025-00087, has been filed and is pending.
• It is noted that there has been First worldwide family litigation filed related to this patent family.

No specific cases for US patent 12371685 were found in a search of CAFC 2026 dockets. The identified litigation is currently a PTAB (Patent Trial and Appeal Board) case.