Invalidity dossier
US 11021703
Methods and kit for characterizing the modified base status of a transcriptome
Current assignee: Cornell University
Added 9/23/2026, 9:53:00 PM
Active provider: DeepSeek · deepseek-flash
Patent summary
Title, assignee, inventors, filing/issue dates, abstract, and a plain-language overview of the claims.
Patent Overview — US11021703B2
Title: Methods and kit for characterizing the modified base status of a transcriptome.
Patent number / application: US11021703B2; application US14/377,680; pre-grant publication US20160060622A1.
Assignee: Cornell University (original assignee; a confirmatory NIH license was recorded 2017-09-29). Inventors: Samie R. Jaffrey, Kate D. Meyer, Christopher E. Mason.
Key dates: Priority date 2012-02-16; filing date 2013-02-18; publication of application 2016-03-03; grant/publication of the patent 2021-06-01; anticipated expiration 2033-02-18. Legal status listed as Active.
Purpose and plain-language scope (from the supplied excerpt): The patent concerns methods and a kit for characterizing the modified base status of a transcriptome — that is, determining where modified bases occur across the collection of RNA transcripts in a sample. The excerpt's indexing shows the subject matter centers on RNA, transcriptome, peaks, antibody, transcripts, and immunoprecipitation, with N(6)-methyladenosine (m6A) appearing in the claims and description. Associated terms include sequencing, nucleotide/nucleoside chemistry, beads (including paramagnetic and magnetic), crosslinking, fragmentation and cleavage, methylation, non-coding RNA and microRNA, poly(A) RNA, 3′/5′ UTRs, FTO, RNA editing, and antibodies/antigens. The abstract reference list also points to applications in disease, diagnosis, and prognosis, with disease mentions including cancer and obesity, and species/tissue mentions including human, mouse, rat, rabbit, and brain.
Source: https://patents.google.com/patent/[US11021703](/patent/US11021703)/en
What the excerpt does not establish: It does not reproduce the actual claim language, the full abstract, the written description, or any prior-art references and their citations. The "prior art keywords" list is an indexing artifact, not a statement of prior art. The excerpt does not establish claim scope, claim count, or which embodiments are claimed versus merely described; the legal status is expressly noted in the source as an assumption, not a legal conclusion. No litigation, ownership-transfer, validity, or prior-art analysis is presented here.
Generated 10/1/2026, 9:33:58 PM
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Litigation summary
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PTAB challenges
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Assignment history
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Prior art
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Obviousness
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Extensions
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Derivative works
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