Invalidity dossier

US 9221897

Human cytomegalovirus neutralizing antibodies and use thereof

Current assignee: Institute for Research in Biomedicine

Added 9/21/2026, 9:32:40 AM

At a glanceNo PTAB challengesNo litigation on file

Active provider: DeepSeek · deepseek-flash

Patent summary

Title, assignee, inventors, filing/issue dates, abstract, and a plain-language overview of the claims.

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Patent Overview: US9221897B2

Title: Human cytomegalovirus neutralizing antibodies and use thereof

Patent Number: US9221897B2

Assignee: Institute for Research in Biomedicine (IRB) — original and current assignee per the supplied listing

Inventors: Antonio Lanzavecchia and Annalisa Macagno

Key Dates:

  • Priority date: 2008-07-16
  • Application number: US14/096,283
  • Filing date: 2013-12-04
  • Publication date (as US20140193428A1): 2014-07-10
  • Grant/publication date (as US9221897B2): 2015-12-29
  • Anticipated expiration: 2029-07-15
  • Legal status: Expired – Fee Related

Purpose and Plain-Language Scope:
The patent concerns human antibodies that neutralize human cytomegalovirus (HCMV), a DNA virus of the herpesvirus family (classification C07K16/089 — Cytomegalovirus; A61P31/22 — antivirals for herpes viruses). The classifications indicate the subject matter covers immunoglobulins against viral material, peptide medicinal preparations, and antiviral/anti-infective therapeutic uses, including antibody-containing compositions and combinations of two or more separate antibodies (A61K2039/507). The classification tags further indicate human (primate) antibody origin, defined epitope binding (including linear epitopes under 20 residues or conformational epitopes), glycosylation features, and various antibody fragments (Fab, Fab', F(ab')2, scFv, VH/VL, CDRs). The listed prior-art keywords are: antibody, seq, hcmv, antibodies, epitope. In plain terms, the patent appears directed to human-derived HCMV-neutralizing antibodies, their epitopes/sequences, and their use in treating or preventing HCMV infection. Family members referenced in the listing include US9365636B1, US9527902B2, US9796771B2, and US9796772B2.

Source: https://patents.google.com/patent/[US9221897](/patent/US9221897)/en

What this excerpt does not establish: The supplied text contains no claims, no sequence listings, no examples, no efficacy or dosing data, and no specification body. It therefore does not establish the actual claimed scope, the specific antibodies or epitopes, or any clinical use. The classification codes and keywords are metadata only and are not a legal characterization of claim scope. Litigation, ownership transfers, validity, and prior art are outside this overview and were not researched.

Generated 10/1/2026, 10:02:11 PM

Cases on file (0)

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Litigation summary

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Proceedings on file (0)

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No PTAB proceedings on file. This patent has not been challenged via IPR, PGR, or CBM. The absence is itself a signal — well-asserted patents eventually attract IPRs. The LLM analysis below may surface filings the ODP feed hasn’t indexed yet.

PTAB challenges

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Assignment history

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Prior art

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Obviousness

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Extensions

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Derivative works

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