Invalidity dossier
US 8438898
Calibrant infusion fluid source preparation
Current assignee: Edwards Lifesciences Corp
Added 9/24/2026, 12:29:38 AM
Active provider: DeepSeek · deepseek-v4-flash
Patent summary
Title, assignee, inventors, filing/issue dates, abstract, and a plain-language overview of the claims.
Patent Overview — US8438898B2
Title: Calibrant infusion fluid source preparation
Patent number / application: US8438898B2; application US12/827,802, filed 2010-06-30.
Assignee: Edwards Lifesciences Corporation (original and current assignee per the source).
Key dates: Priority date 2009-07-01; publication date 2013-05-14; granted 2013-05-14. Legal status is listed as "Expired – Fee Related," with an adjusted expiration of 2031-07-28. The source notes legal status is an assumption, not a legal conclusion.
Inventors: James R. Petisce, Michael J. Higgins, Kristie Trinh, Todd Abraham.
Purpose: The disclosure relates to analyte measuring systems and, more specifically, to methods and systems for preparing a calibrant infusion fluid source (the "calibrant bag") used with an intravenous blood glucose (IVBG) sensor system intended for hospital settings such as the ICU, OR, or step-down ward. Controlling blood glucose is described as vital in critical care, where accuracy and timeliness matter, and where minimally invasive approaches may not track glucose accurately enough for intensive insulin therapy.
Plain-language scope: The patent addresses how to prepare the glucose-containing infusion fluid used to calibrate an IVBG sensor. The source excerpt describes known preparation approaches, including filling an IV bag with saline and a selected amount of glucose at the supplier's location (pre-mixed), and notes that pre-mixed options may require measuring glucose concentration immediately before use. It identifies problems with each known method — for example, that common hospital glucose analyzers are designed for whole blood and/or blood plasma, not a saline-based fluid. The excerpt also provides background on electrochemical (amperometric) biosensors, enzyme electrodes such as glucose oxidase, and the electrochemical reactions underlying analyte measurement.
Source: https://patents.google.com/patent/[US8438898](/patent/US8438898)/en
What the excerpt does not establish: It does not provide the full claims, detailed description, or drawing content; it omits much of the specification (marked as excerpted). It therefore does not establish the precise claimed method steps, the specific embodiments of calibrant preparation, or the full technical details of the described systems. It also does not establish enforceability, claim scope, or the content of any prior art.
Generated 10/1/2026, 9:31:55 PM
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Litigation summary
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PTAB challenges
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Assignment history
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Prior art
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Obviousness
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Extensions
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Derivative works
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