Invalidity dossier
US 6428814
Bioadhesive nanoparticulate compositions having cationic surface stabilizers
Current assignee: Alkermes Pharma Ireland Ltd
Added 9/23/2026, 4:34:18 PM
Active provider: DeepSeek · deepseek-flash
Patent summary
Title, assignee, inventors, filing/issue dates, abstract, and a plain-language overview of the claims.
Patent Overview — US 6,428,814 B1
Title: Bioadhesive nanoparticulate compositions having cationic surface stabilizers
Patent number: US 6,428,814 B1
Application number: US 09/414,159
Inventors: H. William Bosch; Eugene R. Cooper; Simon L. McGurk
Original assignee: Elan Pharma International Ltd. The source lists the current assignee as Alkermes Pharma Ireland Ltd, without analysis of that listing.
Priority date: 1999-10-08
Filing date: 1999-10-08
Publication date: 2002-08-06
Legal status shown: Expired – Fee Related; anticipated expiration 2019-10-08
Purpose and plain-language scope (from the supplied text):
The patent concerns bioadhesive nanoparticulate compositions that use cationic surface stabilizers. The prior-art keywords confirm the core concepts: a composition, nanoparticulate material, "less" (smaller particle sizes), an active agent, and agents generally. Classification entries point to particle-containing preparations, quaternary ammonium compounds, phospholipids/lecithin, polysaccharides and quaternized cellulose derivatives, and vinylpyrrolidone copolymers, consistent with cationic stabilizer chemistry. Classification also includes "ingredients to enhance the sticking of the active ingredients," matching the bioadhesive framing. The source text also references other versions, notably US 2002/0068092 A1, and related filings including PCT/US2000/027434 (WO 2001026635 A2), EP 1217993 B1, JP 4394324 B2, CA 2386782 C, and later US patents US 7,288,267 B2 and US 7,850,995 B2.
What the supplied excerpt does not establish:
It contains no claims, no written description, and no examples. The active agents, particle-size limits, specific cationic stabilizers, dosage forms, or methods of making and using are therefore not established by this text. The assignee listing is expressly disclaimed as unaudited, and no representation is made about ownership, validity, or enforceability.
Generated 10/1/2026, 9:44:22 PM
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Litigation summary
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Proceedings on file (0)
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PTAB challenges
AIA trial proceedings at the USPTO Patent Trial and Appeal Board — IPR, PGR, and CBM. Petitioners, judge panels, claim-level invalidation outcomes from Final Written Decisions, and Federal Circuit appeals. The single most important defensive datapoint after litigation history.
Assignment history
Inventors, original assignee, and the chain of ownership recorded with the USPTO — including the correspondent attorney who recorded each assignment, since shell-LLC chains often share one repeat-player attorney even when the entity names look unrelated. Surfaces NPE / patent-troll patterns: shell-entity transfers, known asserters in the chain, repeat correspondent fingerprints, pre-litigation assignments, and bankruptcy fire-sales.
Prior art
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Obviousness
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Extensions
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Derivative works
Defensive disclosure: derivative variations of each claim designed to render future incremental improvements obvious or non-novel.