Defendant

Ascendis Pharma Growth Disorders A/S

1 case as defendant.

Cases
1
Active
0
1 closed
Filed
2025
Top venue
ITC
1 case
Also appears as a plaintiff in 1 case → View as plaintiff

Company profile

Ascendis Pharma Growth Disorders A/S is a Danish limited company (aktieselskab, CVR 32323677) formed 29 June 2012 and registered at Tuborg Boulevard 12, 2900 Hellerup, Denmark. It is a wholly owned subsidiary of Ascendis Pharma A/S (Nasdaq: ASND), a Danish biopharmaceutical group incorporated in 2006. Danish registry filings show the subsidiary with no independent employees or revenue; it is financed by the parent, which has committed technical and financial support through at least mid-2027, and it reports negative net assets. The parent group reported roughly 1,189 full-time employees (31 Dec 2025), trailing-twelve-month revenue near US$1.2 billion, and a market capitalization in the mid-teens of billions (FT, Yahoo Finance, Simply Wall St).

Operations. The subsidiary sits inside the parent's growth-disorders franchise, built on the TransCon prodrug/sustained-release platform. Group products include SKYTROFA (lonapegsomatropin, once-weekly growth hormone) for pediatric and adult growth hormone deficiency, YORVIPATH (palopegteriparatide) for adult chronic hypoparathyroidism, and YUVIWEL (navepegritide, TransCon CNP) for pediatric achondroplasia, which reached the U.S. market in 2026. Pipeline work includes a CNP-plus-hGH combination (COACH trial), additional growth indications, oncology programs, and a Novo Nordisk metabolic-disease collaboration.

Litigation posture. This is an operating-company commercial dispute, not NPE activity. The two tracked cases are reciprocal: BioMarin Pharmaceutical named the company a respondent in ITC Section 337 investigation 337-TA-1447 (April 2025) over U.S. Reissue Patent 48,267 covering C-type natriuretic peptide variants, while Ascendis and affiliates filed a parallel declaratory-judgment action in the Northern District of California. Venues are the ITC and N.D. Cal — not the Eastern District of Texas.

Context. In late August 2026 the parties announced a global settlement: Ascendis pays BioMarin royalties of 20% of U.S. net sales and 18% of EU, Brazil and South Korean net sales of YUVIWEL through May 2030; BioMarin drops the ITC investigation, and remaining actions in California, Brazil, Denmark, Germany and South Korea are resolved.

BioMarin Pharmaceutical Inc. v. Ascendis Pharma, Inc. et al.

settled/dismissed
Docket:
337-TA-1447
Filed:
2025-04-02

ITC Section 337 investigation titled Certain Drug Products Containing C-Type Natriuretic Peptide Variants, and Components Thereof, brought by BioMarin against Ascendis entities and suppliers regarding TransCon CNP / navepegritide. The asserted patent was U.S. Reissue Patent No. RE48,267; US 8,377,884 was relied on by Ascendis as prior-art Exhibit 32, not asserted. Resolved by a global settlement announced August 30–31, 2026, with the investigation to be dismissed.