Invalidity dossier
US 5580734
Method of producing a physical map contigous DNA sequences
Current assignee: Shire Human Genetics Therapies Inc
Added 9/23/2026, 10:04:41 PM
Active provider: DeepSeek · deepseek-flash
Patent summary
Title, assignee, inventors, filing/issue dates, abstract, and a plain-language overview of the claims.
Patent Overview — US5580734A
Title: "Method of producing a physical map contigous DNA sequences" (spelling as given in the source).
Identifiers and dates (per source): US5580734A; application no. US08/301,872; filed 1994-09-06; granted 1996-12-03; prior art date 1990-07-13 (priority date described in the source as an assumption, not a legal conclusion). Inventors: Douglas A. Treco and Allan M. Miller. Original assignee: Transkaryotic Therapies Inc.; current assignee listed as Shire Human Genetics Therapies Inc. Legal status: Expired – Lifetime, with anticipated expiration 2013-12-03.
Purpose / plain-language scope: The patent concerns producing a physical map of contiguous DNA sequences — that is, assembling overlapping DNA fragments into an ordered, continuous map. According to the source's own indexing, the disclosure centers on homologous recombination, DNA targeting, yeast (Saccharomyces cerevisiae) host cells, plasmids and other vectors, selectable markers, restriction endonucleases, artificial chromosomes (including artificial yeast chromosomes), linear effects, telomeres, and screening. Complementary DNA, cDNA synthesis, DNA ligases, Southern blotting, and restriction fragment length polymorphism techniques also appear among the indexed terms. The abstract field mentions chromosome, screening, and chromosomal effects. The source also records a related priority to US08/443,372 (publication US5869239A) and a later assignment to Shire Human Genetic Therapies, Inc. described as a change of name.
What the excerpt does not establish: The supplied text is an excerpt and omits the abstract, claims, and description bodies. It therefore does not establish the actual claim scope, the specific steps of the method, the precise nature of the "contiguous" map produced, any experimental results, or the identity of cited prior-art references. The term frequencies and "prior art keywords" are automated index annotations, not claim language. Assignee listings, priority/prior-art dates, and legal status are expressly stated in the source as assumptions rather than legal conclusions, and no litigation, ownership-transfer, or validity analysis is undertaken here.
Source: https://patents.google.com/patent/[US5580734](/patent/US5580734)/en
Generated 10/1/2026, 9:33:47 PM
Cases on file (0)
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Litigation summary
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Proceedings on file (0)
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No PTAB proceedings on file. This patent has not been challenged via IPR, PGR, or CBM. The absence is itself a signal — well-asserted patents eventually attract IPRs. The LLM analysis below may surface filings the ODP feed hasn’t indexed yet.
PTAB challenges
AIA trial proceedings at the USPTO Patent Trial and Appeal Board — IPR, PGR, and CBM. Petitioners, judge panels, claim-level invalidation outcomes from Final Written Decisions, and Federal Circuit appeals. The single most important defensive datapoint after litigation history.
Assignment history
Inventors, original assignee, and the chain of ownership recorded with the USPTO — including the correspondent attorney who recorded each assignment, since shell-LLC chains often share one repeat-player attorney even when the entity names look unrelated. Surfaces NPE / patent-troll patterns: shell-entity transfers, known asserters in the chain, repeat correspondent fingerprints, pre-litigation assignments, and bankruptcy fire-sales.
Prior art
Earlier patents, publications, and products that may anticipate or render the claims unpatentable.
Obviousness
Combinations of prior art that suggest the claimed invention would have been obvious under 35 U.S.C. § 103.
Extensions
Patent term adjustments, term extensions, continuations, divisionals, family members, and expiration dates.
Derivative works
Defensive disclosure: derivative variations of each claim designed to render future incremental improvements obvious or non-novel.