Martina Tyreus Hufnal

Martina Tyreus Hufnal is a Principal at Fish & Richardson, where she co-leads the firm's Life Sciences Industry Team, specializing in intellectual property litigation. Her practice areas primarily encompass the pharmaceutical and biotechnology sectors, with extensive experience in Hatch-Waxman litigation, biosimilar cases, and medical device disputes. She also handles patent disputes involving chemical, electrical, and software technologies, including cases related to small molecule and biosimilar protein formulations, gene editing, polymer chemistry, gasoline blending, and load balancing software. She has appeared as local counsel in cases such as Implicit, LLC v. Sonos, Inc. and Intellectual Ventures I LLC v. Canon Inc. et al.

Ms. Hufnal largely represents operating companies, often defending them against infringement claims, particularly branded pharmaceutical companies against generic challenges. She successfully defended Gilead against Merck in a patent infringement case concerning Hepatitis C treatment drugs Sovaldi® and Harvoni®, which involved the reversal of a $2.5 billion verdict. She also achieved an infringement win for Exeltis against generic entry for the oral contraceptive Slynd®, culminating in a favorable ruling and settlement in 2025. Her notable defense work includes co-leading the successful defense of Microsoft against a patent assertion entity. Before joining Fish & Richardson, she practiced IP litigation in Delaware and clerked for Judge Sue L. Robinson in the U.S. District Court for the District of Delaware (2005-2006). Her earlier career also included local counsel work with Richards, Layton & Finger.

Ms. Hufnal possesses significant experience in post-grant proceedings, with clients acknowledging her "prowess in post-grant proceedings". Her expertise extends to Inter Partes Review (IPR) and Post-Grant Review (PGR) proceedings, an area where Fish & Richardson is recognized. She was involved as co-lead counsel for Johnson Matthey in an IPR related to a patent controlling nitrogen oxide emissions.

She earned her J.D. from Washington University School of Law in 2005 and holds a B.S.C.E. in Chemical Engineering from the University of Delaware (2002). She is admitted to practice in Delaware, before the U.S. Patent and Trademark Office, the U.S. Court of Appeals for the Federal Circuit, and the U.S. District Court for the District of Delaware.