Patent 11066656
Prior art
Earlier patents, publications, and products that may anticipate or render the claims unpatentable.
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Prior art
Earlier patents, publications, and products that may anticipate or render the claims unpatentable.
The Google Patents page for US11066656B2 and other related PubChem patent pages provide a "References Cited" section. I will extract the U.S. Patent Documents from these results. It is important to note that the depth of the "brief description" and "which claim(s) it potentially anticipates" will be limited to what can be inferred from the titles and abstracts available in the search snippets, as I do not have direct access to the full text of each cited patent.
Here are the U.S. Patent Documents cited in US11066656B2, based on the provided search results:
Most Relevant Prior Art for US Patent 11066656
Based on the provided Google Patents and PubChem snippets, the following U.S. patent documents are cited as prior art for US11066656. The ability to provide a detailed description and claim anticipation analysis for each is limited by the information available in the search results (primarily titles and abstracts).
I. Direct Parent Patent
- US 9,447,401 B2
- Full Citation: US 9,447,401 B2, "PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF" (issued Sep. 20, 2016).
- Publication/Filing Date: Issued Sep. 20, 2016; filed Dec. 28, 2012 (as U.S. application Ser. No. 13/694,731).
- Brief Description: This patent is explicitly stated as the direct parent of US11066656 (US11066656 is a divisional of US 9,447,401). It covers "PH20 polypeptide variants, formulations and uses thereof," which directly aligns with the subject matter of US11066656.
- Potential Anticipation: As a direct parent, it is highly likely to anticipate all claims (Claims 1-31) of US11066656, particularly regarding the core concept of modified PH20 polypeptides, their formulations, and uses, unless the claims in US11066656 define novel modifications or specific combinations not present in US 9,447,401. Divisional applications typically claim subject matter disclosed in the parent application but not claimed.
II. Other U.S. Patent Documents Cited
The following are additional U.S. patent documents cited as prior art, with descriptions limited to what can be gleaned from their presence in the citation lists. Without access to their full text, specific claim anticipation is difficult to determine precisely, but general areas of relevance can be inferred.
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- Full Citation: US 3,536,809 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: Likely relates to compositions or methods involving enzymes or pharmaceuticals, given its broad classification.
- Potential Anticipation: Could potentially anticipate aspects of pharmaceutical compositions (Claim 25) or general enzymatic uses if it describes hyaluronidase or related enzyme formulations/applications.
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- Full Citation: US 3,598,123 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: Similar to US 3,536,809, likely relates to pharmaceutical or enzyme technologies.
- Potential Anticipation: Similar to US 3,536,809, could anticipate aspects of compositions (Claim 25) or general enzyme uses.
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- Full Citation: US 3,630,200 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: Likely pertains to medical preparations or enzyme-related subject matter.
- Potential Anticipation: Could be relevant to general pharmaceutical compositions (Claim 25) or methods of using enzymes.
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- Full Citation: US 3,710,795 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Similar to other early patents, general aspects of compositions or enzyme applications.
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- Full Citation: US 3,845,770 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could potentially anticipate formulations or methods of using medical preparations.
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- Full Citation: US 3,916,899 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to compositions or medical uses.
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- Full Citation: US 4,002,531 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could address pharmaceutical formulations or enzyme applications.
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- Full Citation: US 4,008,719 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: General relevance to compositions or methods.
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- Full Citation: US 4,044,126 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could be relevant to aspects of pharmaceutical compositions.
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- Full Citation: US 4,179,337 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could address general aspects of medicinal preparations.
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- Full Citation: US 4,364,923 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: General relevance to pharmaceutical formulations or enzyme applications.
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- Full Citation: US 4,414,209 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could be relevant to compositions or methods.
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- Full Citation: US 4,769,027 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations.
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- Full Citation: US 4,952,496 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could potentially anticipate aspects of pharmaceutical compositions.
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- Full Citation: US 5,033,252 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations.
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- Full Citation: US 5,052,558 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could be relevant to methods or compositions.
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- Full Citation: US 5,059,595 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations.
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- Full Citation: US 5,073,543 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could be relevant to pharmaceutical compositions or methods of use.
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- Full Citation: US 5,120,548 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations.
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- Full Citation: US 5,122,614 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could anticipate aspects of compositions or methods.
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- Full Citation: US 5,292,509 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations.
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- Full Citation: US 5,323,907 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could be relevant to pharmaceutical compositions.
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- Full Citation: US 5,324,844 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations or methods.
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- Full Citation: US 5,446,090 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could anticipate aspects of compositions or methods.
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- Full Citation: US 5,591,767 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations.
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- Full Citation: US 5,612,460 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could be relevant to pharmaceutical compositions.
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- Full Citation: US 5,639,476 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations or methods.
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- Full Citation: US 5,643,575 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Could anticipate aspects of compositions or methods.
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- Full Citation: US 5,665,069 A (no title or date explicitly provided in snippets).
- Publication/Filing Date: Not explicitly provided in snippets.
- Brief Description: General medical or enzyme preparation.
- Potential Anticipation: Broad relevance to medical preparations.
US 7,767,429 B2
- Full Citation: US 7,767,429 B2, "Hyaluronidase variants and pharmaceutical composition comprising the same" (issued Aug. 3, 2010).
- Publication/Filing Date: Issued Aug. 3, 2010.
- Brief Description: This patent's title, "Hyaluronidase variants and pharmaceutical composition comprising the same," directly points to the subject matter of hyaluronidase variants and their pharmaceutical compositions. This suggests it would cover modifications to hyaluronidase.
- Potential Anticipation: Given its title, US 7,767,429 B2 is highly relevant and likely anticipates claims related to modified hyaluronidase polypeptides (Claim 1) and pharmaceutical compositions containing them (Claim 25), particularly if it describes variants with increased stability or activity. The specific nature of the modifications claimed in US11066656 (e.g., specific amino acid positions, type of stability) would determine the extent of anticipation.
Important Note on Anticipation (35 U.S.C. § 102):
To definitively determine anticipation under 35 U.S.C. § 102, a detailed comparison of each element of the claims of US11066656 against the full disclosure of each cited prior art document would be necessary. The brief descriptions above are based solely on titles and limited abstract information, and therefore only indicate potential areas of relevance. A document anticipates a claim if it discloses every single element of that claim, either explicitly or inherently.Here is an analysis of the most relevant prior art for US patent 11066656, based on the provided text and search results:
Most Relevant Prior Art for US Patent 11066656
The most directly relevant prior art identified for US patent 11066656 is its parent application, US 9,447,401 B2, as US11066656 is a divisional of this earlier patent. Additionally, US 7,767,429 B2 also appears highly relevant given its title. A number of other, older U.S. patents are also cited.
I. Direct Parent Patent
- Full Citation: US 9,447,401 B2, "PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF"
- Publication/Filing Date: Issued September 20, 2016. The application was filed on December 28, 2012, as U.S. application Ser. No. 13/694,731.
- Brief Description: This patent covers PH20 polypeptide variants, their formulations, and uses. As the direct parent from which US11066656 is a divisional application, it inherently discloses much, if not all, of the subject matter of the current patent. Divisional applications typically claim subject matter disclosed in the parent application but not previously claimed.
- Potential Anticipation (35 U.S.C. § 102): Given its direct lineage and identical title, US 9,447,401 B2 likely anticipates all claims (Claims 1-31) of US11066656. Any novelty in the claims of US11066656 would reside in specific modifications, compositions, or methods that were disclosed but not claimed in US 9,447,401 B2, or in further refinements that distinguish it from the parent's claims.
II. Other Highly Relevant Prior Art
- Full Citation: US 7,767,429 B2, "Hyaluronidase variants and pharmaceutical composition comprising the same"
- Publication/Filing Date: Issued August 3, 2010.
- Brief Description: This patent specifically addresses hyaluronidase variants and pharmaceutical compositions containing them. Its subject matter is very closely related to the core innovations of US11066656, which focuses on modified PH20 hyaluronidase polypeptides with increased stability and/or activity, and their formulations.
- Potential Anticipation (35 U.S.C. § 102): US 7,767,429 B2 has a high likelihood of anticipating claims in US11066656, particularly those concerning:
- Claim 1: Modified PH20 polypeptides exhibiting increased stability or activity, especially if the '429 patent discloses similar types of modifications (amino acid replacements, etc.) that lead to enhanced properties in hyaluronidase variants.
- Claim 25: Pharmaceutical compositions comprising such modified hyaluronidase polypeptides and pharmaceutically acceptable excipients.
- Claims 30 & 31: Methods for identifying or selecting modified hyaluronan-degrading enzymes with increased stability, if the '429 patent describes similar screening or selection methodologies for hyaluronidase variants.
III. Additional U.S. Patent Documents Cited
The following U.S. patents are also cited, but without access to their full text, a specific description and detailed anticipation analysis is limited. Their relevance is inferred from their inclusion in the "References Cited" list, suggesting they represent broader background art in related fields such as pharmaceutical preparations, enzyme technology, or protein modification.
- US 3,536,809 A
- US 3,598,123 A
- US 3,630,200 A
- US 3,710,795 A
- US 3,845,770 A
- US 3,916,899 A
- US 4,002,531 A
- US 4,008,719 A
- US 4,044,126 A
- US 4,179,337 A
- US 4,364,923 A
- US 4,414,209 A
- US 4,769,027 A
- US 4,952,496 A
- US 5,033,252 A
- US 5,052,558 A
- US 5,059,595 A
- US 5,073,543 A
- US 5,120,548 A
- US 5,122,614 A
- US 5,292,509 A
- US 5,323,907 A
- US 5,324,844 A
- US 5,446,090 A
- US 5,591,767 A
- US 5,612,460 A
- US 5,639,476 A
- US 5,643,575 A
- US 5,665,069 A
For these numerous older patents, their titles and full descriptions are not available in the snippets. Therefore, a specific determination of which claims they might anticipate under 35 U.S.C. § 102 cannot be made without further detailed review of each patent's full text. Generally, they represent the state of the art prior to the inventions claimed in US11066656, potentially disclosing general principles of enzyme preparation, pharmaceutical formulation, or broader medical applications.
Generated 5/29/2026, 5:55:21 PM