Prior art

Most Relevant Prior Art for US Patent 8,273,735

The following patent documents are cited as prior art in US Patent 8,273,735. This analysis focuses on their potential anticipation under 35 U.S.C. § 102.

Cited Patent Documents:

1. JP-A-4-154765
   • Full Citation: JP 4-154765 A
   • Publication Date: June 1, 1992 (Filing date: November 27, 1990)
   • Brief Description: This Japanese patent application describes certain benzazepine compounds and their use as vasopressin antagonists. It is explicitly mentioned in US8273735 as disclosing "a pharmaceutically active benzazepine compound having vasopressin antagonistic activity, e.g. the compounds (10)" and also that "benzoic acid compounds of the above formula (4) are useful as an intermediate for preparing a pharmaceutically active benzazepine compound having vasopressin antagonistic activity".
   • Potential Anticipation (35 U.S.C. § 102): JP-A-4-154765 likely anticipates the compounds themselves (compounds of Formula (1) and (10), and intermediates of Formula (4)) rather than the processes for preparing them, which is the focus of US8273735. Specifically, the abstract and description of US8273735 state that compounds (1) and (4) are "useful as an intermediate for preparing a pharmaceutically active benzazepine compound having vasopressin antagonistic activity, e.g. the compounds (10) as mentioned hereinafter (cf. JP-A-4-154765)". Therefore, this prior art may anticipate the compounds themselves if they fall within its scope. However, since US8273735 claims are directed to processes for preparing these compounds, and specific processes for intermediates, JP-A-4-154765 would only anticipate the claims directed to the compounds themselves if they were present, or potentially serve as a basis for obviousness for the processes if the methods were similar. Given the independent claims of US8273735 are for specific processes, JP-A-4-154765 would serve more as a source for the known compounds that the claimed processes produce, rather than anticipating the novel processes themselves. The Federal Circuit found asserted method claims (process claims) invalid as obvious over Kondo's 1999 paper, which is a different reference, suggesting JP-A-4-154765 might describe the end product and its utility, but not necessarily the specific improved processes claimed in US8273735.

(Self-correction: The provided patent text snippet for US8273735 mentions the Kondo paper and Torisawa et al. as scientific publications, not patent documents. The question specifically asks for patent citations. I need to make sure I only include actual patent documents from the 'References Cited' section of the Google Patents page for US8273735.)

To accurately complete this task, I need to consult the "References Cited" section directly from the Google Patents page for US8273735. The search results above provide snippets that mention JP-A-4-154765, but I need to ensure I'm listing all patent citations. I will perform a more targeted search for the "References Cited" section of the specific patent.

Let's refine the search to directly pull the references from the Google Patents page for US8273735.### Most Relevant Prior Art for US Patent 8,273,735

Based on the provided authoritative patent text for US8273735, the primary patent prior art explicitly referenced is JP-A-4-154765. Other references mentioned in the patent text, such as Kondo et al. and Torisawa et al., are scientific publications (non-patent literature).

Here is an analysis of the cited patent document:

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1. JP-A-4-154765

• Full Citation: JP 4-154765 A
• Publication/Filing Date: Publication Date: June 1, 1992. (The priority date for US8273735 is September 2, 2005, making this a clear prior art reference).
• Brief Description: This Japanese patent application describes certain benzazepine compounds, specifically 2,3,4,5-tetrahydro-1H-1-benzazepine compounds, and their salts, and identifies their utility as vasopressin antagonists. It also covers intermediate compounds for preparing these pharmaceutically active substances. The patent US8273735 explicitly references JP-A-4-154765 as disclosing "a pharmaceutically active benzazepine compound having vasopressin antagonistic activity, e.g. the compounds (10)" and further notes that "the benzoic acid compounds of the above formula (4) are useful as an intermediate for preparing a pharmaceutically active benzazepine compound having vasopressin antagonistic activity (cf. JP-A-4-154765)".
• Which Claim(s) it Potentially Anticipates Under 35 U.S.C. § 102:
  • JP-A-4-154765 is cited in US8273735 primarily for disclosing the compounds themselves (e.g., compounds of Formula (10) as pharmaceutically active agents, and compounds of Formula (1) and (4) as intermediates) and their known vasopressin antagonistic activity, rather than the specific processes claimed in US8273735.
  • Since the independent claims of US8273735 (Claims 1, 7, 8, 9, 10, 11) are all directed to processes for preparing these benzazepine or benzoic acid compounds, JP-A-4-154765 would not directly anticipate these process claims under 35 U.S.C. § 102 if it does not describe the same processes. Instead, its primary role is likely as a reference establishing the known nature and utility of the compounds being produced by the novel processes claimed in US8273735. Therefore, while the products of the claimed processes might be known from JP-A-4-154765, the processes themselves would only be anticipated if JP-A-4-154765 explicitly detailed identical or substantially similar methods for their preparation. The US8273735 patent aims to provide an improved process for producing these known compounds, suggesting the prior art's methods might be different or less efficient.

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