Prior art

To identify the most relevant prior art for US patent 12291566, I would typically search for documents cited within the patent itself. Since I cannot directly access the full USPTO file wrapper for live patent data or specific cited references within US12291566B2 beyond what's in the provided Google Patents text (which primarily lists "Prior art keywords" rather than specific patent citations), I will explain the general process and what kind of information would be needed.

The "Prior art keywords" section on the Google Patents page for US12291566B2 lists "seq," "tnf," "antibody," "amino acid," and "human." These are general terms, not specific patent or publication numbers.

To provide the most relevant prior art, the ideal next step would be to consult the "References Cited" section of the issued patent document itself from the USPTO database. This section, typically found on the front page of a granted patent, lists all prior art (patents and non-patent literature) that was considered by the patent examiner during prosecution and/or submitted by the applicant.

Assuming access to the full patent document, for each cited prior art reference, I would then gather:

1. Full Citation: This would include the patent number (for other patents), publication number (for patent applications), or full bibliographic information (for non-patent literature).
2. Publication/Filing Date: This is crucial for determining if a reference is indeed prior art under 35 U.S.C. § 102.
3. Brief Description: A concise summary of what the prior art discloses.
4. Which Claim(s) it potentially anticipates under 35 U.S.C. § 102: This would require a detailed claim-by-claim analysis of US12291566B2 against the disclosures of each prior art document. Anticipation under 35 U.S.C. § 102 means that every element of a claim is found, either explicitly or inherently, in a single prior art reference.

General Guidance on Prior Art and 35 U.S.C. § 102:

35 U.S.C. § 102 outlines the conditions for patentability, specifically regarding novelty. A person is entitled to a patent unless, among other things, the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention.

Without the explicit "References Cited" section from the patent document itself, I cannot provide a specific list of prior art citations and their detailed analysis. The Google Patents page for US12291566B2, while indicating litigation, does not provide a list of cited prior art documents.