Extensions

To determine the patent term adjustments (PTA), patent term extensions (PTE), continuation/divisional applications, related family members, and projected expiration date for US Patent 10793916, I will use the information available from the USPTO and Google Patents.

1. Patent Term Adjustments (PTA):
PTA is granted to compensate for certain delays by the USPTO during the prosecution of a patent application. This includes delays in issuing a first office action, responding to applicant replies, or issuing the patent within a specific timeframe (e.g., three years from filing). The official PTA calculation is included in the Issue Notification Letter and on the face of the issued patent.

To get the precise PTA for US10793916, I would typically consult the patent document itself (which often has a section for "Patent Term Adjustment" on the front page) or the USPTO's Patent Center. As I don't have direct access to a live, interactive USPTO database to pull up the exact PTA calculation, I will note that such information is usually found on the patent's front page.

2. Patent Term Extensions (PTE):
PTE is a different mechanism from PTA and is available under the Hatch-Waxman Act (35 U.S.C. § 156) for patents claiming products (e.g., human drugs, medical devices, food additives) that require pre-market regulatory approval from agencies like the FDA. It aims to restore patent term lost during this approval process. Only one patent can be extended per approved product, and the extension cannot exceed five years or extend the patent more than 14 years from the date of marketing approval.

Given the title "Systems and methods to detect rare mutations and copy number variation," which relates to diagnostic methods and potentially medical devices, it is plausible that Guardant Health Inc. could apply for a PTE if a product covered by the patent requires FDA approval. However, without specific information about an FDA-approved product directly covered by this patent and an associated PTE application, it's not possible to state with certainty if a PTE has been granted or applied for. USPTO typically updates lists of PTE applications and grants. I do not have access to these real-time lists.

3. Continuation Applications, Divisional Applications, and Related Family Members:

• Continuation and Divisional Applications: These are types of continuing applications that claim priority to an earlier-filed "parent" application. A continuation application is filed during the pendency of its parent application and shares the same disclosure. A divisional application is filed when the USPTO determines that an original application contains more than one invention. Both benefit from the filing date of the earliest non-provisional application in the chain.
• Related Family Members: These include parent applications (from which priority is claimed) and child applications (continuations, divisionals, or continuations-in-part) that claim priority to the patent in question.

The Google Patents page for US10793916B2 lists other versions and priority claims, which indicate related family members:

• US20200087735A1 (Publication of US10793916B2, so this is not a separate application but the pre-grant publication).
• Priority to US16/575,128 (this is the application number for US10793916).
• Priority to US16/593,633, which led to US10822663B2 [cite: patent/US10793916B2/en].
• Priority to US16/709,437, which led to US10961592B2 [cite: patent/US10793916B2/en].
• Priority to US16/885,079, which led to US10876171B2 [cite: patent/US10793916B2/en].
• Priority to US16/897,038, which led to US10876172B2 [cite: patent/US10793916B2/en].
• And many more priority claims (US17/068,710, US17/146,359, US17/152,529, US17/210,191, US17/370,941, US17/386,338, US17/696,524, US18/157,249, US18/333,436, US18/426,665, US18/594,336, US18/930,072, US19/088,591, US19/311,988, US19/362,169) indicating a complex family of related applications, including continuations and potentially divisionals. [cite: patent/US10793916B2/en]

4. Projected Expiration Date:
For U.S. utility patents filed on or after June 8, 1995, the patent term generally expires 20 years from the earliest filing date of the application, or of an earlier application to which it claims priority (excluding provisional applications for this calculation). This 20-year term can be adjusted by PTA or extended by PTE.

• Earliest Priority Date: The earliest priority date listed for US10793916B2 is September 4, 2012 [cite: patent/US10793916B2/en].
• Calculation: 20 years from the earliest priority date (September 4, 2012) is September 4, 2032.
• Anticipated Expiration (from Google Patents): Google Patents itself lists an "Anticipated expiration" date of 2033-09-04 [cite: patent/US10793916B2/en]. This discrepancy of one year suggests that there has been a Patent Term Adjustment (PTA) of approximately one year (365 days) added to the base 20-year term. This PTA would be due to delays during the patent's prosecution by the USPTO.

Therefore, the projected expiration date, including the indicated PTA, is September 4, 2033. This calculation assumes no further PTE has been granted.